Zika virus infectionHot
CNS Infections 3898 0
Zika virus is a mosquito-borne flavivirus primarily transmitted by Aedes aegypti mosquitoes (Hayes, 2009; CDC, 2016 ) and to a lesser extent by Aedes albopictus mosquitoes.
Epilepsy 2540 0
see Neonatal seizures
Epilepsy Classification IndexHot
Epilepsy 4373 0
The International League Against Epilepsy (ILAE) Commission on Classiﬁcation and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy.
Neonatal epileptic seizuresHot
Neonatal Neurology 8751 0
Neonatal epileptic seizures occur from birth to the end of the neonatal period.This is the most vulnerable of all the other periods of life for the development of epileptic seizures, particularly in the first 1 or 2 days from birth. Neonatal seizures differ from those of older children and adults. They may be short-lived events lasting for just a few days, but they often signify serious malfunction or damage of the immature brain, and constitute a neurological emergency that demands urgent diagnosis and management. Most neonatal seizures are acute (pro-voked, occasional, reactive) symptomatic seizures caused by an acute illness...
Pharmacopoeia 3983 0
Zonisamide is a synthetic 1,2-benzisoxazole derivative (1,2-benzisoxazole-3-methanesulfonamide).
Pharmacopoeia 4439 0
Vigabatrin (γ-vilyl-GABA; 4-amino-hex-5-enoic acid) was a result of a rational approach to design compounds that enhance the effect of the inhibitory neurotransmitter GABA.1-16
Pharmacopoeia 7851 0
Levetiracetam is a single enantiomer, (S)-α-ethyl-2-oxo-pyrrolidine acetamide. Levetiracetam, licensed in 1999, is probably the best of all the newer AEDs1-7. It is chemically unrelated to any of the other current AEDs.
Pharmacopoeia 13006 0
Lamotrigine is a 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine of the phenyltriazine class. It was first licensed for clinical practice in 1991. Lamotrigine is one of the best newer AEDs, although there are now concerns for its use in women and myoclonic epilepsies.
Pharmacopoeia 9682 0
Lacosamide is a functionalized amino acid (R)-2-acetamido-N-benzyl-3-methoxypropionamide. It is one of the latest AEDs to be licensed (at the end of 2008), under the brand name Vimpat.
Pharmacopoeia 4424 0
Gabapentin (1-[aminomethyl]-cyclohexaneacetic acid) first received marketing approval as an adjunctive AED for the treatment of focal epilepsies in 1993.1,2